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Safety Data Sheet (SDS) APC Anti-mouse CD36 Antibody     Product Data Sheet (PDF)    
APC Anti-mouse CD36 Antibody
1113055 25 µg $90.00       
1113060 100 µg $260.00       
Clone: HM36
Isotype: Armenian Hamster IgG
Reactivity: Mouse
Immunogen: Full length version of the protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested

Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application References:

1. Hamilton R F, 2006. J. Biol. Chem. 281:34218.
2. Stuart L M, 2007. J. Biol. Chem. doi:10.1074/jbc.M702887200.

Thioglycollate-elicited BALB/c mouse peritoneal macrophages

Thioglycollate-elicited BALB/c mouse peritoneal macrophages stained with HM36 APC



Description:

CD36 is a 85 kD glycoprotein, also known as FAT, gpIIIb, or gpIV. It is a member of the class B scavenger receptor family, expressed on platelets, monocytes, macrophages, megakaryocytes, microvasculature, dendritic cells and mammary endothelial cells. The primary ligands for CD36 have been reported to be oxidized low density lipoprotein, anionic phospholipids, and collagens I, IV, and V. CD36 acts as a scavenger receptor thus promoting the removal of apoptotic neutrophils and other apoptotic bodies, as well as clearance of defective erythrocytes.

Other Names: FAT, gpIIIb, gpIV
Structure: Scavenger receptor superfamily, 85 kD
Distribution: Platelets, monocytes, macrophages, microvascular and mammary endothelial cells
Function: Scavenger receptor, recognition and phagocytosis of apoptotic neutrophils, adhesion
Ligand Receptor: Oxidized low density lipoprotein, anionic phospholipids, collagen I, IV, and V
Antigen References:

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Greenwalt DE, et al. 1992. Blood 80:1105.
3. Endemann G, et al. 1993. J. Biol. Chem. 268:11811.