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Safety Data Sheet (SDS) Biotin Anti-mouse CD84 Antibody     Product Data Sheet (PDF)    
Biotin Anti-mouse CD84 Antibody
1214015 50 µg $75.00       
Clone: mCD84.7
Isotype: Armenian Hamster IgG
Reactivity: Mouse
Immunogen: Mouse CD84-Fc fusion protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application:

FC - Quality tested

Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References:

1. Romero X, et al. 2005. J. Immunol. 174:7033.
2. Fedeli M, et al. 2009. J. Immunol. 183:2506. PubMed

C57BL/6 mouse splenocytes stained with

C57BL/6 mouse splenocytes stained with biotinylated mCD84.7, followed by Sav-PE



Description:

CD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production.

Other Names: GR6, Ly9b, SLAMF5
Structure: 64-82 kD glycoprotein, SLAM family, CD2 subset of Ig superfamily
Distribution: B cells, monocytes, thymocytes, platelets, subset of T cells
Function: Homophilic adhesion, T cell activation
Ligand Receptor: CD84
Antigen References:

1. de la Fuente MA, et al. 1997. Blood 90 (6):2398.
2. Tangye SG, et al. 2002. Eur. J. Immunol. 32(6):1640.
3. Tangye SG, et al. 2003. J. Immunol. 171:2485.
4. Martin M, et al. 2001. J. Immunol. 167:3668.
5. Romero X, et al. 2005. J. Immunol. 174:7033.