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Safety Data Sheet (SDS) Purified Anti-rat CD5 Antibody     Product Data Sheet (PDF)    
Purified Anti-rat CD5 Antibody
1617505 100 µg $100.00       
Clone: OX-19
Isotype: Mouse IgG1, κ
Reactivity: Rat
Immunogen: Rat thymocyte lentil lectin-binding glycoproteins
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application:

FC - Quality tested
IHC - Reported in the literature

Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References:

1. Dallman MJ, et al. 1984. Eur. J. Immunol. 14:260.
2. Vemeer LA, et al. 1994. Eur. J. Immunol. 24:585.

LOU rat splenocytes stained with

LOU rat splenocytes stained with OX-19 purified, followed by anti-mouse IgG PE



Description:

CD5 is a 67 kD glycoprotein, also known as Lyt-1, Ly-1 or Ly-12. It is a member of the scavenger receptor superfamily and primarily expressed on thymocytes and mature peripheral T lymphocytes, but not on NK cells, intestinal intraepithelial gamma/delta T cells. A CD5+ B cell subset (B-1) has not been characterized in that rat.

Other Names: Ly-1, Tp67, Leu-1, T1, Lyt-1
Structure: CD5 is a 67 kD glycoprotein of scavenger receptor superfamily. It is expressed on thymocytes, T cells and small subset of B cells.
Distribution: Expressed on thymocytes, peripheral T cells, and some thymic dendritic cells. It should be noted that a CD5+ subset of B cells has not been characterized in the rat by OX-19. Most gamma/delta T cells do not express CD5.
Function: Important in T-B cell interaction.
Ligand Receptor: CD72
Antigen References:

1. Vermeer LA, et al. 1994. Eur. J. Immunol. 24:585.