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Safety Data Sheet (SDS) FITC Anti-rat RT1D Antibody     Product Data Sheet (PDF)    
FITC Anti-rat RT1D Antibody
1627025 100 µg $125.00       
Clone: OX-17
Isotype: Mouse IgG1, κ
Reactivity: Rat
Immunogen: Wistar rat splenocyte membrane extract
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested

Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application References:

1. Mayrhofer G et al. 1983. Eur J Immunol 13:1122. Fukumoto T et al. 1982. Eur J Immunol 12:237

LOU rat splenocytes stained with

LOU rat splenocytes stained with OX-17 FITC



Description:

The OX-17 antibody reacts with a non-polymorphic determinant of rat MHC class II antigen.It is found primarily on the surface of B lymphocytes,macrophages,dendritic cells and other antigen presenting cells.

Other Names: Rat MHC class II
Structure: The rat MHC class II RT1D is equivalent to mouse I-E antigen. It consists of two chain structure around 28-32 kd, non-covalently linked each other.
Distribution: The rat MHC class II antigen is expressed on antigen presenting cells, including B cells, macrophages and dendritic cells.
Function: Present antigenic peptide to engage TCR
Ligand Receptor: Presenting antigenic peptide to TCR
Antigen References:

1. Mayrhofer G et al. 1983. Eur J Immunol 13:1122. Fukumoto T et al. 1982. Eur J Immunol 12:237