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Safety Data Sheet (SDS) FITC Anti-rat CD200 Receptor Antibody     Product Data Sheet (PDF)    
FITC Anti-rat CD200 Receptor Antibody
1624525 100 µg $125.00       
Clone: OX-102
Isotype: Mouse IgG1, κ
Reactivity: Rat
Immunogen: Membrane fraction of thioglycollate-elicited rat peripheral cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.5% BSA (origin U.S.)
Preparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested

Application Notes:

Additional reported applications(for the relevant formats) include: immunoprecipitation, Western blotting, and immunohistochemical staining of acetone-fixed frozen sections.

Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References:

1. Wright GJ, et al. 2000.Immunity 13:233.
2. Dick AD, et al. 2001. Invest Ophthalmol Vis Sci 42:170.

LOU rat peritoneal cells stained

LOU rat peritoneal cells stained with OX-102 FITC



Description:

CD200 receptor is a 60-100 kD type I transmembrane glycoprotein, also known as OX-2R or CD200R. It is a member of the immunoglobulin superfamily that is primarily expressed on macrophages/monocytes, granulocytes, mast cells, subsets of T (memory T) and B (memory B and plasmablasts) cells. The interaction of CD200R with its ligand, CD200, plays roles in down-regulation of myeloid cells activity and inhibition of dendritic cell-induced Th1 cytokine production, as well as in modulating microglial activation.

Other Names: OX-2R, CD200R