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Safety Data Sheet (SDS) PE Anti-mouse CD24 Antibody     Product Data Sheet (PDF)    
PE Anti-mouse CD24 Antibody
1292515 50 µg $75.00       
1292520 200 µg $195.00       
Clone: 30-F1
Isotype: Rat IgG2c, κ
Reactivity: Mouse
Immunogen: Mouse thymus/spleen
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested

Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application References:

1. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (FC)

C57BL/6 mouse splenocytes stained with

C57BL/6 mouse splenocytes stained with 30-F1 PE



Description:

CD24 is a 35-45 kD protein, also known as Heat Stable Antigen (HSA), Ly-52, or Nectadrin. It is a GPI-linked sialoglycoprotein expressed on lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, dendritic cells, hematopoietic stem cells, and neurons. CD24 expression varies during T and B cell differentiation and is a useful marker for delineating various lymphocyte developmental stages. CD24 serves as an adhesion or costimulatory molecule involved in T and B lymphocyte activation and differentiation by homophilic binding or binding to CD62P.

Other Names: Heat Stable Antigen (HSA), HsAg, Ly-52, Nectadrin
Structure: GPI-linked sialoglycoprotein, 35-45 kD.
Distribution: Lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, dendritic cells, and neurons.
Function: Regulate B and T cell proliferation and differentiation.
Ligand Receptor: P-selectin, CD24
Antigen References:

1. Li YS, et al. 1993. J. Exp. Med. 178:951.
2. Aigner S, et al. 1995. Int. Immunol. 7:1557.
3. Hunte BE, et al. 1998. Eur. J. Immunol.. 28:3850.
4. Auerbach R, et al. 1996. Stem Cells 14:269.
5. Allman DM, et al. 1993. J. Immunol.. 151:4431.