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Safety Data Sheet (SDS) PE/Cy7 Anti-mouse Podoplanin Antibody     Product Data Sheet (PDF)    
PE/Cy7 Anti-mouse Podoplanin Antibody
1237055 25 µg $120.00       
1237060 100 µg $265.00       
Clone: 8.1.1
Isotype: Syrian Hamster IgG
Reactivity: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested

Application Notes:

Additional reported applications (for the relevant formats) include: immunohistochemistry6.

Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References:

1. Farr A, et al. 1992. J. Histochem. Cytochem. 40:651.
2. Farr AG, et al. 1992. J. Exp. Med. 176:1477.
3. Bekiaris V, et al. 2008. J. Immunol. 180:6768.
4. Algars A, et al. 2011. Blood 117:4387. PubMed
5. Reis VO, et al. 2012. Immunobiology. 217:831. PubMed
6. Kaji C, et al. 2012. Acta. Histochem. Cytochem. 45:227. (IHC)
7. Kretschmer S, et al. 2013. PLoS One. 8:e52201. PubMed.

Mouse thymic epithelial stromal cell

Mouse thymic epithelial stromal cell line TE-71 stained with 8.1.1 PE/Cy7



Description:

The mucin-type glycoprotein podoplanin is thought to be involved in the development of the lymphatic vascular system. Podoplanin is named after its expression in the kidney glomerular epithelial cells (podocytes). It has a potential role in tumor progression.

Other Names: T1a, gp38, stromal cell marker
Structure: 43 Kd glycosylated type-1 transmembrane protein. Mucin-type protein.
Distribution: Expressed on epithelial and mesothelial cells.
Antigen References:

1. Farr A, et al. 1992. J. Histochem. Cytochem. 40:651.
2. Schacht V, et al. 2005. Am. J. Pathol. 166:913.


This product or portions thereof is manufactured under license from GE Healthcare under U.S. Patent Numbers 5,268,486; 5,569,587; 5,627,027 and patents or pending applications that are continuations, continuations-in-part, re-examinations, divisionals, reissues or foreign equivalents thereof. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE.
COMMERCIAL USE shall include:

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  • sale, lease, license or other grant of rights to use this Material or any material derived or produced from it;
  • use of this material to perform services for a fee for third parties.

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