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Safety Data Sheet (SDS) PE Anti-mouse TCR Vbeta9 Antibody     Product Data Sheet (PDF)    
PE Anti-mouse TCR Vβ9 Antibody
1299015 25 µg $100.00       
1299020 100 µg $215.00       
Clone: MR10-2
Isotype: Mouse IgG1, κ
Reactivity: Mouse
Immunogen: Mouse T-cell hybridoma 2BR18
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested

Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application References:

1. Utsunomiya Y, et al. 1991. Eur. J. Immunol. 21:1007. (FC)

C57BL/6 mouse splenocytes stained with

C57BL/6 mouse splenocytes stained with TCR Vβ9 (MR10-2) PE and CD3 (145-2C11) APC



Description:

Vβ9 T cell receptor (TCR Vβ9) is a variant of TCR β chain and, along with TCR α chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition through interaction with MHC-peptide complex to initiate T cell-mediated immune responses. Murine Vβ9 cells recognize the Mtv-43, Mtv-44, and exogenous MMTV (SW) Mls-1 superantigens.Mice bearing a and c haplotypes have Vβ9 gene deletion.

Other Names: Vβ9 T-cell receptor, T cell receptor beta 9
Structure: Member of the immunoglobulin superfamily, Vβ9 is a variant of the TCR β chain which associates with the TCR α chain to form the TCR heterodimer.
Distribution: Subset of TCR αβ+ T cells
Function: Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune responses.
Ligand Receptor: MHC-peptide complex
Antigen References:

1. Ortman RA, et al. 1994. J. Immunol. 152:4175.
2. Niimi N, et al. 1994. Immunogenetics 40:312.
3. Pied s, et al. 1997. Int. Immunol. 9:17.